Take the tablet as soon as possible, preferably within the first 12 hours, and no later than 72 hours (3 days) after having unprotected sex. ESLEVELLE can be taken at any time during your menstrual cycle, assuming you are not already pregnant or think you may be pregnant. Do not chew the tablet, but swallow it whole with water. Do not delay taking the tablet. The tablet works best the sooner it is taken after you have had unprotected sex.